In this preliminary study, the variability of COX-2 overexpression in cervical premalignant lesions was assessed.
NSAIDs and COX-2 inhibitors show anti-cancer activities in many cancer cells.
Aspirin showed strongest inhibitory effects on viability and survival of YD-8 cells.
Aspirin treatment resulted in severe cell shrinkage and nuclear DNA fragmentation in YD-8 cells.
Modeling – Million Dollar Baby
This movie is the story about woman whom boxing is all of her life.
After the movie is showed, the number of women who is interested in boxing is increase.
♠ 암세포 생육 저해 효능 실험
각종 암세포에 대한 생육 저해활성의 검정은 SRB(sulforhodamine B) assay(Skehan et al., 1990)에 의하여 다음과 같이 수행하였다.
암 세포주는 인간의 간암세포인 Hep3B(hepatocellular carcinoma, human), 폐암세포인 A549(lung carcinoma, human), 유방암세포인 MCF7(brest adenocarcinoma, pleural effusion, human
Ⅰ. 서론
어떤 통증이라도 이상적인 치료는 원인을 제거하는데 있다. 원인제거는 때로는 가능하지만, 진단 후 원인에 대한 적절한 치료가 시작된 다음에도 통증완화(pain subsides)전에 지연기간(lag period)이 있는 경우가 더 많다. 더욱이 너무 통증이 심해서 급히 효과적인 진통제가 필요한 경우도 있다(
Introduction
Attention is important in everyday living. To process abundant information in the environment in the most efficient way with limited cognitive resource, we use selective attention which requires allocating attention to relevant information and ignoring irrelevant information. Inhibiting task-irrelevant information is crucial for optimal processing. Cognitive control refers to a mech
Effects
외국과는 달리 지방이나 단백질 보다 탄수화물이 많은 한국 사람들에게 딱 맞는 다이어트 보조제이다. 실제 과체중 및 비만(BMI 26) 이상인 성인대상으로, 가르시니아카보이자 껍질추출물(HCA) 섭취 시 복부피하지방, 내장지방 감소(Subcutaneous fat, visceral fat reduction)가 인체시험을 통해 확인됐다.
3
1.1.2. Cyclooxygenase-prostanoid cascade
Figure 1.1. Metabolism of arachidonic acid
Despite the diverse chemical structure of aspirin-like drugs, the antinociceptive effect of NSAIDs is mainly due totheir common property of inhibiting cyclooxygenases involved in the formation of prostanoids. Prostanoids areformed by most cells and act as autocrine and paracrine lipid mediators. They are n
Lipopolysaccharides (LPS), also known as lipoglycans,
are large molecules consisting of a lipid and a polysaccharide
joined by a covalent bond; they are found in the outer
membrane of Gram-negative bacteria, act as endotoxins and
elicit strong immune responses in animals.
LPS is the major component of the outer membrane of
Gram-negative bacteria, contributing greatly to the structu
* 위암을 일으키는 요인
① Diet
위는 인체의 대표적인 소화기관이다. 위와 관련된 질환, 특히 만성적 노출로서 야기되는 Cancer는 평소 식습관에 가장 밀접한 관련이 있다고 볼 수 있다.
( 위암의 위험인자 : nitrate-rich food, smoked food, high salt diet, high starch diet, spicy food, broiled food, fatty food, alcohol, etc.)
Some food make ROS (Inflammation)
Nitrate-rich food
High salt diet
Spicy food
Fatty food
Alcohol
Some food make Benzo(a)pyrene
Smoked food
Broiled food
Barry J Marshall reveals the relation of H. pylori to gastric adenocarcinoma and lymphoma.
The relation of Helicobacter pylori to gastric adenocarcinoma
and lymphoma, Marshall BJ, Windsor HM 1984
Nobel prize in physiology or medici